PENGARUH SINBIOTIK KEFIR TEPUNG PISANG BATU (<em>Musa balbisiana</em>) TERHADAP KADAR GLUKOSA DARAH TIKUS SINDROM METABOLIK

Main Article Content

Dhea Marliana Salsabila
Taufik Maryusman
Iin Fatmawati

Abstract

Metabolic syndrome begins with insulin resistance characterized by hyperglycemia. Synbiotic kefir banana (Musa balbisiana Colla) flour reduces blood glucose level. This study was conducted to analyze the effects of synbiotic kefir banana (M. balbisiana) flour on blood glucose level of metabolic syndrome rats. This study used 24 Sprague Dawley.rats which were divided into four groups, i.e. negative control was given standard diet, positive control was given high fat fructose diet (HFFD), treatment I (PI) and treatment II (PII) were given HFFD and synbiotic kefir banana (M. balbisiana) flour 1.8 mL 200 g־¹ rat BW per day (PI) and 3.6 mL 200 g־¹ rat BW per day (PII), respectively, for three weeks. The result showed a significant difference (p=0.000) in blood glucose after giving synbiotic kefir banana (M. balbisiana) flour. Synbiotic kefir banana (M. balbisiana) flour reduced blood glucose level in metabolic syndrome rats.

Keywords: banana flour, blood glucose level, kefir, metabolic syndrome, synbiotic 

ABSTRAK

Sindrom metabolik diawali resistensi insulin yang ditandai hiperglikemia. Sinbiotik kefir tepung pisang batu (M. balbisiana) menurunkan kadar glukosa darah. Penelitian ini dilakukan untuk menganalisis pengaruh sinbiotik kefir tepung pisang batu (M. balbisiana) terhadap kadar glukosa darah tikus sindrom metabolik. Penelitian ini menggunakan 24 tikus Sprague Dawley yang dibagi menjadi empat kelompok, yaitu kontrol negatif yang diberi pakan standar, kontrol positif yang diberi high fat fructose diet (HFFD), dan perlakuan I (PI) serta perlakuan II (PII) yang masing-masing diberi HFFD dan sinbiotik kefir tepung pisang batu (M. balbisiana) 1,8 mL 200 g־¹ BB tikus per hari (PI) dan 3,6 mL 200 g־¹ BB tikus per hari (PII) selama tiga minggu. Hasil menunjukkan perbedaan kadar glukosa darah setelah pemberian sinbiotik kefir tepung pisang batu (M. balbisiana) secara signifikan (p=0,000). Sinbiotik kefir tepung pisang batu (M. balbisiana) menurunkan kadar glukosa darah tikus sindrom metabolik.

Article Details

How to Cite
Salsabila, D. M., Maryusman, T., & Fatmawati, I. (2020). PENGARUH SINBIOTIK KEFIR TEPUNG PISANG BATU (<em>Musa balbisiana</em>) TERHADAP KADAR GLUKOSA DARAH TIKUS SINDROM METABOLIK. Jurnal Bioteknologi & Biosains Indonesia (JBBI), 7(1), 18-27. https://doi.org/10.29122/jbbi.v7i1.3730
Section
Research Articles
Author Biographies

Dhea Marliana Salsabila, Universitas Pembangunan Nasional Veteran Jakarta

Program Studi S1 Ilmu Gizi - Fakultas Ilmu Kesehatan

Taufik Maryusman, Universitas Pembangunan Nasional Veteran Jakarta

Program Studi S1 Ilmu Gizi - Fakultas Ilmu Kesehatan

Iin Fatmawati, Universitas Pembangunan Nasional Veteran Jakarta

Program Studi S1 Ilmu Gizi - Fakultas Ilmu Kesehatan

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