Pengaruh Rasio HA/TCP terhadap Karakteristik Komposit BCP-Gelatin-CMC sebagai Bahan Injectable Bone Substitute

Authors

  • Mochammad Dachyar Effendi Pusat Teknologi Material, Badan Pengkajian dan Penerapan Teknologi
  • Nandang Suhendra Pusat Teknologi Material, Badan Pengkajian dan Penerapan Teknologi

DOI:

https://doi.org/10.29122/jitm.v1i2.3837

Keywords:

injectable bone subtitute, hydroxyapatite, komposit keramik-polimer, kerusakan tulang

Abstract

Penambahan bahan semen tulang kedalam rongga tulang dapat menjadi salah satu alternatif untuk mencegah kerusakan tulang akibat osteoporosis. Kelemahan utama dari bahan implant ortopedik berbasis hydroksiapatit sinter adalah bahan dalam bentuk solid dimana dalam aplikasi pembedahan, sulit untuk mengisi rongga tulang dengan ukuran tertentu. Alternatif yang nyaman untuk bahan pengisi tulang suspensi adalah dengan  menggunakan bahan Injectable bone substitute. Dalam studi ini dipelajari komposisi material Injectable Bone substitute dengan matrik berupa polimer CMC-gelatin dan HA/TCP sebagai filler. Dilakukan variasi rasio Hidroksiapatit (HA) / tri-calcium phosphate (TCP) (70:30; 50:50; 40:60)  untuk  mempelajari pengaruhnya terhadap sifat-sifat fisik dan mekanik campuran. Hasil uji FTIR menunjukkan gugus fungsi fosfat (PO43-) gugus fungsi karboksil dan gugus fungsi NH2 yang merujuk kepada  bahan penyusunnya. Peningkatan porositas karena perubahan morfologi dikonfirmasi oleh gambar mikroskop polaritas. Hasil uji tekan menunjukkan berkurangnya  nilai kuat tekan dengan bertambahnya konsentrasi TCP dalam campuran. Semua kelompok uji menunjukkan kemiripan struktural dengan tulang cancellous dalam sifat porositas dan kekuatan mekanik.

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Published

2020-01-30

Issue

Vol. 1 No. 2 (2019)

Section

Articles

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